Exendin 3 (9-39) is a gastrointestinal motility modulating peptide fragment of exendin-3. This peptide acts as an antagonist at glucagon-like peptide 1 (GLP-1) receptors, increasing spontaneous contractions in colon circular muscle. This peptide inhibits the effects of exendin-4 and other GLP-1 agonists. Exendin-3 was originally found in Heloderma lizards.
| Cas No. | 133514-43-9 |
|---|---|
| Purity | ≥95% |
| Formula | C149H234N40O47S |
| Formula Wt. | 3369.83 |
| Synonym | 9-39-Exendin 3(Heloderma horridum) (9CI); Exendin 3 (9-39) |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | E9418 MSDS PDF |
|---|---|
| Info Sheet | E9418 Info Sheet PDF |
Amato A, Baldassano S, Liotta R, et al. Exogenous glucagon-like peptide-1 reduces contractions in human colon circular muscle. J Endocrinol. 2014 Jan 17. [Epub ahead of print]. PMID: 24443715.
Hu G, Zhang Y, Jiang H, et al. Exendin-4 attenuates myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein expression. Cardiol J. 2013;20(6):600-4. PMID: 24338536.
