Description
GalantideisanonselectivepeptideantagoNISTatthegalaninreceptor.Galantideinhibitsopioid-inducedantinociceptioninvivo.Galantideexhibitsneuromodulatory,cognitionenhancing,andgastrointestinalmotilitymodulatingactivities.Inanimalmodels,galantideimprovesmemoryfunctioninsocialrecognitiontasks.Additionally,thiscompoundinducescontractionsingastricsmoothmuscle.
References
SunYG,YuLC.Interactionsofgalaninandopioidsinnociceptivemodulationinthearcuatenucleusofhypothalamusinrats.RegulPept.2005Jan15;124(1-3):37-43.PMID:15544839.
KorolkiewiczRP,KonstanskiZ,RekowskiP,etal.MechanismofthecontractileeffectsofgalantideandGalanin(1-14)[alpha-aminobutyricacid]scyliorhinin-Iinratisolatedfundusstrips.MedSciMonit.2002Jan;8(1):BR19-23.PMID:11782668.
ArlettiR,BenelliA,CavazzutiE,etal.Galantideimprovessocialmemoryinrats.PharmacolRes.1997Apr;35(4):317-9.PMID:9264048.