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商品详细LKT/GHRELIN, HUMAN/G2868/1 mg
LKT/GHRELIN, HUMAN/G2868/1 mg
LKT/GHRELIN, HUMAN/G2868/1 mg
商品编号: G2868-1mg
品牌: lktlabs
市场价: ¥8820.00
美元价: 5292.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References

Description

Ghrelin is an endogenous peptide hormone that regulates feeding behavior, energy homeostasis, and secretion of growth hormone, growth hormone-releasing factor (GHRF/GHRH), and somatostatin. Ghrelin counteracts the effects of leptin, exhibiting orexigenic activity and increasing feeding behavior such as food intake and body weight. Ghrelin activates eNOS in endothelial cells, stimulating activation of AMPK and Akt. Ghrelin also enhances stress-induced fear responding in vivo and increases long-term potentiation (LTP) and dendritic spine synapse formation; it also exhibits cognition enhancing activity, improving spatial learning and memory in other in vivo models.

Product Info

Cas No.

258279-04-8

Purity

≥98%

Formula

C149H249N47O42

Formula Wt.

3370.9

Synonym

Lenomorelin

Solubility

Soluble in 1% acetic acid (1mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G2868 MSDS PDF

Info Sheet

G2868 Info Sheet PDF

References

Meyer RM, Burgos-Robles A, Liu E, et al. A ghrelin-growth hormone axis drives stress-induced vulnerability to enhanced fear. Mol Psychiatry. 2013 Oct 15. [Epub ahead of print]. PMID: 24126924.

Xu X, Jhun BS, Ha CH, Jin ZG. Molecular mechanisms of ghrelin-mediated endothelial nitric oxide synthase activation. Endocrinology. 2008 Aug;149(8):4183-92. PMID: 18450953.

Diano S, Farr SA, Benoit SC, et al. Ghrelin controls hippocampal spine synapse density and memory performance. Nat Neurosci. 2006 Mar;9(3):381-8. PMID: 16491079.

Tschöp M, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature. 2000 Oct 19;407(6806):908-13. PMID: 11057670.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂