GinsenosideF1isatriterpenesaponinoriginallyfoundinspeciesofPanaxthatexhibitscytoprotectiveandanti-apoptoticactivities,inhibitingUV-inducedcelldeathandapoptosisbydownregulatingexpressionofBcl-2andpreventingcleavageofPARP.Thiscompoundalsodecreasesgapjunctioncommunicationinvitro.
| CasNo. | 53963-43-2 |
|---|---|
| Purity | ≥98% |
| Formula | C36H62O9 |
| FormulaWt. | 638.87 |
| IUPACName | (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-[(2R)-6-methyl-2-[(6R,10R,12S,13R,14R,17S)-3,6,12-trihydroxy-4,4,10,14,17-pentamethyl-2,3,5,6,7,8,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-5-en-2-yl]oxyoxane-3,4,5-triol |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | 4°C |
|---|---|
| ShipTemp | Ambient |
| MSDS | G3460MSDSPDF |
|---|---|
| InfoSheet | G3460InfoSheetPDF |
LeeEH,ChoSY,KimSJ,etal.GinsenosideF1protectshumanHaCaTkeratinocytesfromultraviolet-B-inducedapoptosisbymaintainingconstantlevelsofBcl-2.JInvestDermatol.2003Sep;121(3):607-13.PMID:12925222.
ZhangYW,DouDQ,ZhangL,etal.EffectsofginsenosidesfromPanaxginsengoncell-to-cellcommunicationfunctionmediatedbygapjunctions.PlantaMed.2001Jul;67(5):417-22.PMID:11488454.
