Ginsenoside F1 is a triterpene saponin originally found in species of Panax that exhibits cytoprotective and anti-apoptotic activities, inhibiting UV-induced cell death and apoptosis by downregulating expression of Bcl-2 and preventing cleavage of PARP. This compound also decreases gap junction communication in vitro.
| Cas No. | 53963-43-2 |
|---|---|
| Purity | ≥98% |
| Formula | C36H62O9 |
| Formula Wt. | 638.87 |
| IUPAC Name | (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-[(2R)-6-methyl-2-[(6R,10R,12S,13R,14R,17S)-3,6,12-trihydroxy-4,4,10,14,17-pentamethyl-2,3,5,6,7,8,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-5-en-2-yl]oxyoxane-3,4,5-triol |
| Appearance | White to off white powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | G3460 MSDS PDF |
|---|---|
| Info Sheet | G3460 Info Sheet PDF |
Lee EH, Cho SY, Kim SJ, et al. Ginsenoside F1 protects human HaCaT keratinocytes from ultraviolet-B-induced apoptosis by maintaining constant levels of Bcl-2. J Invest Dermatol. 2003 Sep;121(3):607-13. PMID: 12925222.
Zhang YW, Dou DQ, Zhang L, et al. Effects of ginsenosides from Panax ginseng on cell-to-cell communication function mediated by gap junctions. Planta Med. 2001 Jul;67(5):417-22. PMID: 11488454.
