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当前位置: 首页 > 产品中心 > clinical_research > LKT/GINSENOSIDE F2/G3461/1 mg
商品详细LKT/GINSENOSIDE F2/G3461/1 mg
LKT/GINSENOSIDE F2/G3461/1 mg
LKT/GINSENOSIDE F2/G3461/1 mg
商品编号: G3461-1mg
品牌: lktlabs
市场价: ¥2240.00
美元价: 1344.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

GinsenosideF2isatriterpenesaponinoriginallyfoundinspeciesofPanaxthatexhibitsanti-obesityandanticancerchemotherapeuticactivities.GinsenosideF2inhibitshaircellapoptosis,decreasingexpressionofTGF-β2,SCAP,andSREBPinvivo.GinsenosideF2alsodecreaseslipidaccumulationinADIpocytes,suppressingexpressingofPPARγandperilipinandinhibitingAdipogenesis.Thiscompoundalsoinducesformationofacidicvesicles,autophagy,andmitochondrialapoptosisinbreastcancerstemcells;additionally,itdecreasestumorgrowthinanimalmodelsofglioblastoma.

ProductInfo

CasNo.

62025-49-4

Purity

≥98%

Formula

C42H72O13

FormulaWt.

785.03

IUPACName

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol

Appearance

Whitetooffwhitepowder

ShippingandStorage

StoreTemp

4°C

ShipTemp

Ambient

Downloads

MSDS

G3461MSDSPDF

InfoSheet

G3461InfoSheetPDF

References

ShinHS,ParkSY,HwangES,etal.GinsenosideF2reduceshairlossbycontrollingapoptosisthroughthesterolregulatoryelement-bindingproteincleavageactivatingproteinandtransforminggrowthfactor-βpathwaysinadihydrotestosterone-inducedmousemodel.BiolPharmBull.2014;37(5):755-63.PMID:24789999.

SirajFM,SathishkumarN,KimYJ,etal.GinsenosideF2possessesanti-obesityactivityviabindingwithPPARγandinhibitingadipocytedifferentiationinthe3T3-L1cellline.JEnzymeInhibMedChem.2014Mar25.[Epubaheadofprint].PMID:24666293.

MaiTT,MoonJ,SongY,etal.GinsenosideF2inducesapoptosisaccompaniedbyprotectiveautophagyinbreastcancerstemcells.CancerLett.2012Aug28;321(2):144-53.PMID:22326284.

QuanLH,PiaoJY,MinJW,etal.BiotransformationofGinsenosideRb1toProsapogenins,GypenosideXVII,GinsenosideRd,GinsenosideF2,andCompoundKbyLeuconostocmesenteroidesDC102.JGinsengRes.2011Sep;35(3):344-51.PMID:23717079.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂