Description
GinsenosideF2isatriterpenesaponinoriginallyfoundinspeciesofPanaxthatexhibitsanti-obesityandanticancerchemotherapeuticactivities.GinsenosideF2inhibitshaircellapoptosis,decreasingexpressionofTGF-β2,SCAP,andSREBPinvivo.GinsenosideF2alsodecreaseslipidaccumulationinADIpocytes,suppressingexpressingofPPARγandperilipinandinhibitingAdipogenesis.Thiscompoundalsoinducesformationofacidicvesicles,autophagy,andmitochondrialapoptosisinbreastcancerstemcells;additionally,itdecreasestumorgrowthinanimalmodelsofglioblastoma.