LKT/GINSENOSIDE F2/G3461/5 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/GINSENOSIDE F2/G3461/5 mg

LKT/GINSENOSIDE F2/G3461/5 mg

商品编号： G3461-5mg

品牌： lktlabs

市场价： ¥5600.00

美元价： 3360.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Product ID G3461

Cas No. 62025-49-4

Purity ≥98%

Description
Product Info
Shipping and Storage
Downloads
References

Description

Ginsenoside F2 is a triterpene saponin originally found in species of Panax that exhibits anti-obesity and anticancer chemotherapeutic activities. Ginsenoside F2 inhibits hair cell apoptosis, decreasing expression of TGF-β2, SCAP, and SREBP in vivo. Ginsenoside F2 also decreases lipid accumulation in adipocytes, suppressing expressing of PPARγ and perilipin and inhibiting adipogenesis. This compound also induces formation of acidic vesicles, autophagy, and mitochondrial apoptosis in breast cancer stem cells; additionally, it decreases tumor growth in animal models of glioblastoma.

Product Info

Cas No.	62025-49-4
Purity	≥98%
Formula	C₄₂H₇₂O₁₃
Formula Wt.	785.03
IUPAC Name	(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol
Appearance	White to off white powder

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	G3461 MSDS PDF
Info Sheet	G3461 Info Sheet PDF

References

Shin HS, Park SY, Hwang ES, et al. Ginsenoside F2 reduces hair loss by controlling apoptosis through the sterol regulatory element-binding protein cleavage activating protein and transforming growth factor-β pathways in a dihydrotestosterone-induced mouse model. Biol Pharm Bull. 2014;37(5):755-63. PMID: 24789999.

Siraj FM, Sathishkumar N, Kim YJ, et al. Ginsenoside F2 possesses anti-obesity activity via binding with PPARγ and inhibiting adipocyte differentiation in the 3T3-L1 cell line. J Enzyme Inhib Med Chem. 2014 Mar 25. [Epub ahead of print]. PMID: 24666293.

Mai TT, Moon J, Song Y, et al. Ginsenoside F2 induces apoptosis accompanied by protective autophagy in breast cancer stem cells. Cancer Lett. 2012 Aug 28;321(2):144-53. PMID: 22326284.

Quan LH, Piao JY, Min JW, et al. Biotransformation of Ginsenoside Rb1 to Prosapogenins, Gypenoside XVII, Ginsenoside Rd, Ginsenoside F2, and Compound K by Leuconostoc mesenteroides DC102. J Ginseng Res. 2011 Sep;35(3):344-51. PMID: 23717079.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂