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当前位置: 首页 > 产品中心 > clinical_research > LKT/GINSENOSIDE RB2/G3553/25 mg
商品详细LKT/GINSENOSIDE RB2/G3553/25 mg
LKT/GINSENOSIDE RB2/G3553/25 mg
LKT/GINSENOSIDE RB2/G3553/25 mg
商品编号: G3553-25mg
品牌: lktlabs
市场价: ¥17980.00
美元价: 10788.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

GinsenosideRb2isatriterpenesaponinoriginallyfoundinspeciesofPanax(ginseng)thatexhibitsanti-osteoporotic,antioxidative,antiviral,anti-hyperlipidemic,anti-metastatic,anti-angiogenic,andanticancerchemotherapeuticactivities.Invivo,ginsenosideRb2decreaseslevelsofmalondialdehydeandincreaseslevelsofglutathione,improvingbonemicroarchitectureandbonemineraldensity.Inotheranimalmodels,thiscompounddecreasesvirustitersandprotectsagainstinfectionofhemagglutinatingvirusofJapan.InADIpocytes,ginsenosideRb2decreaseslevelsofcholesterolandtriglyceridesandincreasesexpressionofSREBP.Inuterineendometrialcancercells,ginsenosideRb2decreaseexpressionofmatrixmetalloproteinase2(MMP2),suppressivecellularinvasion;thiscompoundalsoinhibitsneovascularizationandtumorgrowthinanimalmodelsofmelanoma.

ProductInfo

CasNo.

11021-13-9

Purity

≥84%

Formula

C53H90O22

FormulaWt.

1079.27

IUPACName

(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Synonym

GinsenosideC

MeltingPoint

197-199°C

Solubility

Solubleinwater.

Appearance

WhitePowder

ShippingandStorage

StoreTemp

4°C

ShipTemp

Ambient

Downloads

MSDS

G3553MSDSPDF

InfoSheet

G3553InfoSheetPDF

References

HuangQ,GaoB,JieQ,etal.Ginsenoside-Rb2displaysanti-osteoporosiseffectsthroughreducingoxidativedamageandbone-resorbingcytokinesduringosteogenesis.Bone.2014Jun13.[Epubaheadofprint].PMID:24933344.

YooYC,LeeJ,ParkSR,etal.Protectiveeffectofginsenoside-Rb2fromKoreanredginsengonthelethalinfectionofhaemagglutinatingvirusofJapaninmice.JGinsengRes.2013Mar;37(1):80-6.PMID:23717160.

KimEJ,LeeHI,ChungKJ,etal.Theginsenoside-Rb2lowerscholesterolandtriacylglycerollevelsin3T3-L1adipocytesculturedunderhighcholesterolorfattyacidsconditions.BMBRep.2009Apr30;42(4):194-9.PMID:19403041.

FujimotoJ,SakaguchiH,AokiI,etal.Inhibitoryeffectofginsenoside-Rb2oninvasivenessofuterineendometrialcancercellstothebasementmembrane.EurJGynaecolOncol.2001;22(5):339-41.PMID:11766734.

SatoK,MochizukiM,SaikiI,etal.InhibitionoftumorangiogenesisandmetastasisbyasaponinofPanaxginseng,ginsenoside-Rb2.BiolPharmBull.1994May;17(5):635-9.PMID:7522731.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂