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当前位置: 首页 > 产品中心 > clinical_research > LKT/GINSENOSIDE RC/G3455/1 mg
商品详细LKT/GINSENOSIDE RC/G3455/1 mg
LKT/GINSENOSIDE RC/G3455/1 mg
LKT/GINSENOSIDE RC/G3455/1 mg
商品编号: G3455-1mg
品牌: lktlabs
市场价: ¥2240.00
美元价: 1344.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

GinsenosideRcisatriterpenesaponinoriginallyfoundinspeciesofPanaxthatexhibitsantioxidative,anti-aging,antinociceptive,andanti-diabeticactivities.GinsenosideRcinhibitsphosphorylationofFoxo1,inhibitsAMPK,activatesPI3K/Aktsignaling,andincreaseslevelsofcatalase,decreasingoxidativestress.GinsenosideRcalsoinducesantinociceptioninanimalmodelsofwrithingandformalin-inducedpain,potentiallythroughactivityontransientreceptorpotentialvanilloid1(TRPV1)channels.Inotheranimalmodels,ginsenosideRcactivatesAMPKandp38MAPK,increasingglucoseuptake.Additionally,thiscompoundincreasesthelifespanofCaenorhaBDitiselegans.

ProductInfo

CasNo.

11021-14-0

Purity

≥98%

Formula

C53H90O22

FormulaWt.

1079.27

IUPACName

2-[2-[[17-[2-[6-[[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl]oxy-6-methylhept-5-en-2-yl]-12-hydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Synonym

PanaxosideRC

Appearance

Whitepowder

ShippingandStorage

StoreTemp

4°C

ShipTemp

Ambient

Downloads

MSDS

G3455MSDSPDF

InfoSheet

G3455InfoSheetPDF

References

KimDH,ParkCH,ParkD,etal.GinsenosideRcmodulatesAkt/FoxO1pathwaysandsuppressesoxidativestress.ArchPharmRes.2014Jun;37(6):813-20.PMID:23918648.

LeeMS,HwangJT,KimSH,etal.GinsenosideRc,anactivecomponentofPanaxginseng,stimulatesglucoseuptakeinC2C12myotubesthroughanAMPK-dependentmechanism.JEthnopharmacol.2010Feb17;127(3):771-6.PMID:19961916.

LeeJH,ChoiSH,KwonOS,etal.Effectsofginsenosides,activeingredientsofPanaxginseng,ondevelopment,growth,andlifespanofCaenorhabditiselegans.BiolPharmBull.2007Nov;30(11):2126-34.PMID:17978487.

JungSY,ChoiS,KoYS,etal.Effectsofginsenosidesonvanilloidreceptor(VR1)channelsexpressedinXenopusoocytes.MolCells.2001Dec31;12(3):342-6.PMID:11804333.

ShinYH,JungOM,NahJJ,etal.Ginsenosidesthatproducedifferentialantinociceptioninmice.GenPharmacol.1999Jun;32(6):653-9.PMID:10401990.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂