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商品详细LKT/GINSENOSIDE RC/G3455/5 mg
LKT/GINSENOSIDE RC/G3455/5 mg
LKT/GINSENOSIDE RC/G3455/5 mg
商品编号: G3455-5mg
品牌: lktlabs
市场价: ¥5600.00
美元价: 3360.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References

Description

Ginsenoside Rc is a triterpene saponin originally found in species of Panax that exhibits antioxidative, anti-aging, antinociceptive, and anti-diabetic activities. Ginsenoside Rc inhibits phosphorylation of Foxo1, inhibits AMPK, activates PI3K/Akt signaling, and increases levels of catalase, decreasing oxidative stress. Ginsenoside Rc also induces antinociception in animal models of writhing and formalin-induced pain, potentially through activity on transient receptor potential vanilloid 1 (TRPV1) channels. In other animal models, ginsenoside Rc activates AMPK and p38 MAPK, increasing glucose uptake. Additionally, this compound increases the life span of Caenorhabditis elegans.

Product Info

Cas No.

11021-14-0

Purity

≥98%

Formula

C53H90O22

Formula Wt.

1079.27

IUPAC Name

2-[2-[[17-[2-[6-[[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl]oxy-6-methylhept-5-en-2-yl]-12-hydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Synonym

Panaxoside RC

Appearance

White powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

G3455 MSDS PDF

Info Sheet

G3455 Info Sheet PDF

References

Kim DH, Park CH, Park D, et al. Ginsenoside Rc modulates Akt/FoxO1 pathways and suppresses oxidative stress. Arch Pharm Res. 2014 Jun;37(6):813-20. PMID: 23918648.

Lee MS, Hwang JT, Kim SH, et al. Ginsenoside Rc, an active component of Panax ginseng, stimulates glucose uptake in C2C12 myotubes through an AMPK-dependent mechanism. J Ethnopharmacol. 2010 Feb 17;127(3):771-6. PMID: 19961916.

Lee JH, Choi SH, Kwon OS, et al. Effects of ginsenosides, active ingredients of Panax ginseng, on development, growth, and life span of Caenorhabditis elegans. Biol Pharm Bull. 2007 Nov;30(11):2126-34. PMID: 17978487.

Jung SY, Choi S, Ko YS, et al. Effects of ginsenosides on vanilloid receptor (VR1) channels expressed in Xenopus oocytes. Mol Cells. 2001 Dec 31;12(3):342-6. PMID: 11804333.

Shin YH, Jung OM, Nah JJ, et al. Ginsenosides that produce differential antinociception in mice. Gen Pharmacol. 1999 Jun;32(6):653-9. PMID: 10401990.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂