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当前位置: 首页 > 产品中心 > clinical_research > LKT/GINSENOSIDE RE/G3457/1 mg
商品详细LKT/GINSENOSIDE RE/G3457/1 mg
LKT/GINSENOSIDE RE/G3457/1 mg
LKT/GINSENOSIDE RE/G3457/1 mg
商品编号: G3457-1mg
品牌: lktlabs
市场价: ¥2240.00
美元价: 1344.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

GinsenosideReisatriterpenesaponinoriginallyfoundinspeciesofPanaxthatexhibitsantioxidative,anti-ulcerative,anti-inflammatory,neuroprotective,anxiolytic,antidepressant,anti-diabetic,anti-allergic,cardioprotective,andimmunostimulatoryactivities.GinsenosideReinhibitsformationofgastricmucosallesionsinvivobyincreasingmucosalsecretion,decreasingneutrophilinfiltration,andsuppressingmyeloperoxidaseandxanthineoxidaseactivity.Inanimalmodelsofimmunization,ginsenosideReactsasanadjuvant,increasingtheCD4+:CD8+cellratio,increasingantibodytiters,andincreasinglevelsofIL-4,IL-10,IL-12,andIFN-γ.GinsenosideReimprovesheartrate,perfusionpressure,bloodflow,andcardiacoutputinanimalmodelsofmyocardialischemia/reperfusion.Additionally,ginsenosideReinhibitshistaminereleaseinmastcellsanddecreasesLPS-stimulatedproductionofCOX-2andiNOSinmicroglia.InADIpocytes,thiscompoundactivatesPPARγsignaling,inducesAdipogenesis,andincreasesglucoseuptake.Invivo,ginsenosideReinhibitsstress-inducedanxiety,depression,andcognitivedeficits.

ProductInfo

CasNo.

52286-59-6

Purity

≥98%

Formula

C49H84O17

FormulaWt.

947.18

IUPACName

(2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,10R,12R,13S,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol

Synonym

PanaxosideRE;GinsenosideB2

Solubility

Solubleinethanol(5mg/ml),DMSO(15mg/ml),andDMF(20mg/ml).Insolubleinwater.

Appearance

WhiteCrystalPowder

ShippingandStorage

StoreTemp

4°C

ShipTemp

Ambient

Downloads

MSDS

G3457MSDSPDF

InfoSheet

G3457InfoSheetPDF

References

SuX,PeiZ,HuS.GinsenosideReasanadjuvanttoenhancetheimmuneresponsetotheinactivatedrABIesvirusvaccineinmice.IntImmunopharmacol.2014Jun;20(2):283-9.PMID:24680943.

LeeS,KimMG,KoSK,etal.ProtectiveeffectofginsenosideReonacutegastricmucosallesioninducedbycompound48/80.JGinsengRes.2014Apr;38(2):89-96.PMID:24748832.

LimKH,LimDJ,KimJH.Ginsenoside-Reamelioratesischemiaandreperfusioninjuryintheheart:ahemodynamicsapproach.JGinsengRes.2013Jul;37(3):283-92.PMID:24198653.

GaoY,YangMF,SuYP,etal.GinsenosideRereducesinsulinresistancethroughactivationofPPAR-γpathwayandinhibitionofTNF-αproduction.JEthnopharmacol.2013May20;147(2):509-16.PMID:23545455.

BaeHM,ChoOS,KimSJ,etal.Inhibitoryeffectsofginsenosidereisolatedfromginsengberryonhistamineandcytokinereleaseinhumanmastcellsandhumanalveolarepithelialcells.JGinsengRes.2012Oct;36(4):369-74.PMID:23717138.

LeeKW,JungSY,ChoiSM,etal.EffectsofginsenosideReonLPS-inducedinflammatorymediatorsinBV2microglialcells.BMCComplementAlternMed.2012Oct26;12:196.PMID:23102375.

LeeB,ShimI,LeeH,etal.EffectofginsenosideReondepression-andanxiety-likebehaviorsandcognitionmemorydeficitinducedbyrepeatedimmobilizationinrats.JMicrobiolBiotechnol.2012May;22(5):708-20.PMID:22561867.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂