LKT/SALSALATE/S0244/25 g-免疫在线蚂蚁淘旗下平台

商品详细LKT/SALSALATE/S0244/25 g

LKT/SALSALATE/S0244/25 g

商品编号： S0244-25g

品牌： lktlabs

市场价： ¥880.00

美元价： 528.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDS0244

CasNo.552-94-3

Purity≥95%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Salsalateissprodrugofsalicylicacidcomposedoftwosalicylatemoleculesattachedbyanesterbond.Salsalateactsasanon-steroidalanti-inflammatorydrug(NSAID),producingweak,reversIBLeinhibitionofCOX-1andCOX-2.Salsalateprimarilyactsasananalgesic,butalsoexhibitsanti-diabeticactivityaswell.SalsalatedecreasesbloodglucoselevelsandincreasesADIponectinlevels.Thiscompoundalsoinhibitsexpressionofinsulinresistance-inducingSelenoproteinP,potentiallymediatedbyactivationofAMPKandphosphorylationofFoxo1α.Salsalateactsasananti-inflammatoryinthetreatmentofrheumatoidarthritis,asitinhibitsIκBkinaseandactivationofNF-κB.Additionally,salsalateimprovesglucosetoleranceanddownregulates11β-hydroxysteroiddehydrogenase1(11β-HSD1)activityinvisceraladiposeinclinicalandinvivosettings.

ProductInfo

CasNo.	552-94-3
Purity	≥95%
Formula	C₁₄H₁₀O₅
FormulaWt.	258.23
ChemicalName	2-(2-hydroxybenzoyl)oxybenzoicacid
IUPACName	2-(2-hydroxybenzoyl)oxybenzoicacid
MeltingPoint	147°C
Appearance	WhiteCrystalPowder

ShippingandStorage

StoreTemp	4°C
ShipTemp	Ambient

Downloads

InfoSheet	S0244InfoSheetPDF

References

JungTW,ChoiHY,LeeSY,etal.SalsalateandAdiponectinImprovePalmitate-InducedInsulinResistanceviaInhibitionofSelenoproteinPthroughtheAMPK-FOXO1αPathway.PLoSOne.2013Jun18;8(6):e66529.PMID:23825542.

NixonM,WakeDJ,LivingstoneDE,etal.Salicylatedownregulates11β-HSD1expressioninadiposetissueinobesemiceandinhumans,mediatinginsulinsensitization.Diabetes.2012Apr;61(4):790-6.PMID:22357964.

McCartyMF.Salsalatemayhavebroadutilityinthepreventionandtreatmentofvasculardisordersandthemetabolicsyndrome.MedHypotheses.2010Sep;75(3):276-81.PMID:20080359.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂