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当前位置: 首页 > 产品中心 > clinical_research > LKT/NEUROMEDIN B, PIG/N1980/2 mg
商品详细LKT/NEUROMEDIN B, PIG/N1980/2 mg
LKT/NEUROMEDIN B, PIG/N1980/2 mg
LKT/NEUROMEDIN B, PIG/N1980/2 mg
商品编号: N1980-2mg
品牌: lktlabs
市场价: ¥3420.00
美元价: 2052.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References

Description

Neuromedin B is an endogenous bombesin-related peptide that binds BB receptors, displaying the greatest affinity for the BB1 receptor. Neuromedin B exhibits anorexigenic and cardiomodulatory activities, decreasing food intake, inducing bradycardia, and slowing gastric emptying in vivo. Neuromedin B also activates ERK1/2 signaling, increasing osteoblast proliferation and bone formation. Additionally, neuromedin B increases secretion of luteinizing hormone (LH) and gonadotropin-releasing hormone (GnRH) in vitro and in vivo.

Product Info

Cas No.

87096-84-2

Purity

≥95%

Formula

C52H73N15O12S

Formula Wt.

1132.3

Chemical Name

1-glycine-2-L-asparagine-3-L-leucine-4-de-L-glutamine-7-L-threonine-Ranatensin

IUPAC Name

(2S)-2-[(2-aminoacetyl)amino]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[2-[[(2S)-1-[[1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]butanediamide

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

N1980 Info Sheet PDF

References

Boughton CK, Patel SA, Thompson EL, et al. Neuromedin B stimulates the hypothalamic-pituitary-gonadal axis in male rats. Regul Pept. 2013 Nov 10;187:6-11. PMID: 24120470.

Saito H, Nakamachi T, Inoue K, et al. Autocrine effects of neuromedin B stimulate the proliferation of rat primary osteoblasts. J Endocrinol. 2013 Apr 15;217(2):141-50. PMID: 23428580.

Sayegh AI. The role of bombesin and bombesin-related peptides in the short-term control of food intake. Prog Mol Biol Transl Sci. 2013;114:343-70. PMID: 23317790.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂