Octaneuropeptide exhibits anorexigenic activity and may also display epileptogenic potential. Octaneuropeptide is a C-terminal fragment of octadecaneuropeptide, a derivative of diazepam-binding inhibitor (DBI). Octaneuropeptide increases intracellular Ca2+ levels in astrocytes in a PLC-dependent manner.
| Purity | ≥98% |
|---|---|
| Formula | C41H74N12O11 |
| Formula Wt. | 911.1 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | O0978 Info Sheet PDF |
|---|
Leprince J, Oulyadi H, Vaudry D, et al. Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN. Design of a potent endozepine antagonist. Eur J Biochem. 2001 Dec;268(23):6045-57. PMID: 11732998.
Vezzani A, Serafini R, Stasi MA, et al. Epileptogenic activity of two peptides derived from diazepam binding inhibitor after intrahippocampal injection in rats. Epilepsia. 1991 Sep-Oct;32(5):597-603. PMID: 1655399.
