Ranatensinisapeptideoriginallyfoundinamphibianskinthatexhibitsgastrointestinalmotilitymodulatingactivity.RanatensinstimulatesCl-secretioninthejejunuminaGRP-relatedmanner.Ranatensinalsostimulatessecretionofgastrin,pancreaticpolypeptide,andgastricacidinanimalmodels.
| CasNo. | 29451-71-6 |
|---|---|
| Purity | ≥98% |
| Formula | C61H85N16O13S |
| FormulaWt. | 1281.5 |
| ChemicalName | Pyroglutamyl-valyl-prolyl-glutaminyl-tryptophyl-alanyl-valyl-glycyl-histidyl-phenylalanyl-methionylamide |
| IUPACName | N-[1-[[1-[[1-[[2-[[1-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[1-[3-methyl-2-[(5-oxopyrrolidine-2-carbonyl)amino]butanoyl]pyrrolidine-2-carbonyl]amino]pentanediamide |
| Solubility | Solubleinwater. |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | R0250InfoSheetPDF |
|---|
ChandanR,NewellSM,BrownDR.Actionsofgastrin-releasingpeptideandrelatedmammalianandamphibianpeptidesoniontransportintheporcineproximaljejunum.RegulPept.1988Oct;23(1):1-14.Erratumin:RegulPept1989Mar;24(3):312.PMID:3238049.
ModlinIM,LamersCB,WalshJH.Stimulationofcaninepancreaticpolypeptide,gastrin,andgastricacidsecretionbyranatensin,litorin,bombesinnonapeptideandsubstanceP.RegulPept.1981Jan;1(4):279-88.PMID:6166964.
