LKT/CEFTRIAXONE DISODIUM HEMIHEPTAHYDRATE/C1637/250 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/CEFTRIAXONE DISODIUM HEMIHEPTAHYDRATE/C1637/250 mg

LKT/CEFTRIAXONE DISODIUM HEMIHEPTAHYDRATE/C1637/250 mg

商品编号： C1637-250mg

品牌： lktlabs

市场价： ¥1480.00

美元价： 888.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDC1637

CasNo.104376-79-6

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Ceftriaxoneisathirdgenerationβ-lactamcephalosporinantibiotic.Ceftriaxoneexhibitsantibacterialefficacyagainstgrampositiveandgramnegativebacteria,inhibitingpenicillinbindingproteinactivitytopreventpeptidoglycansynthesisandbacterialcellwallformation.Ceftriaxoneisalsoneuroprotective.Thiscompounddisplayscognitionenhancingbenefit,suppressingtraumaticbraininjury-inducedbrainedemaandcognitivefunctiondeficitsinanimalmodelsbydecreasingautophagyandupregulatingexpressionofglutamatetransporterGLT-1;thisalsoresultsinprotectioninanimalmodelsofHuntington’sdiseaseandattenuatesthedevelopmentofdependenceandabstinence-inducedwithdrawalinanimalmodelsofsubstanceabuse.

ProductInfo

CasNo.	104376-79-6
Purity	≥98%
Formula	C₁₈H₁₆N₈O₇S₃Na₂•7/2H₂O
FormulaWt.	661.60
ChemicalName	(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)-thio]methyl]-5-thia-1-azABIcyclo[4.2.0]oct-2-ene-2-carboxylicacidDisodiumSaltHemiheptahydrate
IUPACName	disodium;(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(2-methyl-6-oxido-5-oxo-1,2,4-triazin-3-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;hydrate
Synonym	Ceftriaxonedisodiumslathemiheptahydrate;Rocefin;Rocephine
MeltingPoint	>155°C(dec.)
Solubility	Solubleinwater(40g/100ml).DMSO1mg/mL.

ShippingandStorage

StoreTemp	4°C
ShipTemp	Ambient

Downloads

MSDS	C1637MSDSPDF
InfoSheet	C1637InfoSheetPDF

References

CuiC,CuiY,GaoJ,etal.Neuroprotectiveeffectofceftriaxoneinaratmodeloftraumaticbraininjury.NeurolSci.2014May;35(5):695-700.PMID:24277205.

SariY,PrietoAL,BartonSJ,etal.Ceftriaxone-inducedup-regulationofcorticalandstriatalGLT1intheR6/2modelofHuntington"sdisease.JBiomedSci.2010Jul27;17:62.PMID:20663216.

RawlsSM,CavalloF,CapassoA,etal.Thebeta-lactamantibioticceftriaxoneinhibitsphysicaldependenceandabstinence-inducedwithdrawalfromcocaine,amphetamine,methamphetamine,andclorazepateinplanarians.EurJPharmacol.2008Apr28;584(2-3):278-84.PMID:18342307.

BarriereSL,FlahertyJF.Third-generationcephalosporins:acriticalevaluation.ClinPharm.1984Jul-Aug;3(4):351-73.PMID:6432420.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂