Description
Chalconeisanenoneonwhichavarietyofstructuresarebased.Chalconederivativestypicallyexhibitanti-inflammatory,antioxidative,neuroprotective,analgesic,anticancer,andanti-parasiticactivities.
Chalconeisanenoneonwhichavarietyofstructuresarebased.Chalconederivativestypicallyexhibitanti-inflammatory,antioxidative,neuroprotective,analgesic,anticancer,andanti-parasiticactivities.
CasNo. | 94-41-7 |
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Purity | ≥97% |
Formula | C15H12O |
FormulaWt. | 208.26 |
ChemicalName | 1,3-Diphenyl-2-propen-1-one |
IUPACName | (E)-1,3-diphenylprop-2-en-1-one |
Synonym | Chalkone;trans-Benzylideneacetophenone |
MeltingPoint | 54-57°C |
Solubility | Insolubleinwater.Slightlysolubleinethanol. |
Appearance | LightYellowCrystalPowder |
StoreTemp | Ambient |
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ShipTemp | Ambient |
MSDS | C2800MSDSPDF |
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InfoSheet | C2800InfoSheetPDF |
WuJZ,ChengCC,ShenLL,etal.SyntheticChalconeswithPotentAntioxidantABIlityonH2O2-InducedApoptosisinPC12Cells.IntJMolSci.2014Oct14;15(10):18525-18539.PMID:25318055.
JantanI,BukhariSN,AdekoyaOA,etal.StudiesofsyntheticchalconederivativesaspotentialinhibitorsofsecretoryphospholipaseA2,cyclooxygenases,lipoxygenaseandpro-inflammatorycytokines.DrugDesDevelTher.2014Sep16;8:1405-18.PMID:25258510.
ABDellatifKR,ElshemyHA,SalamaSA,etal.Synthesis,characterizationandBIOLOGicalevaluationofnovel4"-fluoro-2"-hydroxy-chalconederivativesasantioxidant,anti-inflammatoryandanalgesicagents.JEnzymeInhibMedChem.2014Sep8:1-8.PMID:25198887.
KarthikeyanC,NarayanaMoorthyNS,RamasamyS,etal.AdvancesinChalconeswithAnticancerActivities.RecentPatAnticancerDrugDiscov.2014Aug19.[Epubaheadofprint].PMID:25138130.
ShivahareR,KorthikuntaV,ChandasanaH,etal.Synthesis,structure-activityrelationships,andbiologicalstudiesofchromenochalconesaspotentialantileishmanialagents.JMedChem.2014Apr24;57(8):3342-57.PMID:24635539.