Clarithromycinisamacrolideantibioticthatbinds23SrRNAonthebacterial50Sribosomalsubunit,inhibitingproteintranslationandsynthesis.ClarithromycinisclinicallyusedtotreatrespiratoryinfectionsanddisplaysefficacyprimarilyagainstgrampositivebacteriaandHelicobacterpylori.
| CasNo. | 81103-11-9 |
|---|---|
| Purity | ≥95% |
| Formula | C38H69NO13 |
| FormulaWt. | 747.95 |
| ChemicalName | 6-O-Methylerythromycin |
| IUPACName | (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione |
| Synonym | Biaxin;Cyllind;Klacid;MaclADIn;Naxy;Veclam;Zeclar |
| MeltingPoint | 217-220°C(dec) |
| Solubility | Solubleinacetone,DMSO(18mg/mL). |
| Appearance | WhiteCrystalPowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | C4502MSDSPDF |
|---|---|
| InfoSheet | C4502InfoSheetPDF |
Cobos-TriguerosN,AtekaO,PitartC,etal.Macrolidesandketolides.EnfermInfeccMicrobiolClin.2009Aug-Sep;27(7):412-8.PMID:19625112.
HaoQ,LiY,ZhangZJ,etal.Newmutationpointsin23SrRNAgeneassociatedwithHelicobacterpyloriresistancetoclarithromycininnortheastChina.WorldJGastroenterol.2004Apr1;10(7):1075-7.PMID:15052698.
