Clinafloxacinisafluoroquinoloneantibioticthatisclinicallyusedtotreatrespiratoryinfections;itdisplaysantibacterialefficacybyinhibitingDNAgyraseandtopoisomeraseIV.Clinafloxacindisplaysbroadspectrumactivity,inhibitinggrowthofActinobacillus,Pasturella,Mannheima,andHistophilus.
| CasNo. | 105956-99-8 |
|---|---|
| Purity | ≥98% |
| Formula | C17H17ClFN3O3•HCl |
| FormulaWt. | 402.24 |
| ChemicalName | 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylicacidhydrochloride |
| IUPACName | 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylicacid |
| Synonym | AM-1091;CI-960;PD-12739 |
| MeltingPoint | 263-265°C(dec.) |
| Appearance | Yellowishcrystallinepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | C4535MSDSPDF |
|---|---|
| InfoSheet | C4535InfoSheetPDF |
SweeneyMT,QuesnellR,TiwariR,etal.Invitroactivityandrodentefficacyofclinafloxacinforbovineandswinerespiratorydisease.FrontMicrobiol.2013Jun14;4:154.PMID:23785362.
BallP,FernaldA,TillotsonG.Therapeuticadvancesofnewfluoroquinolones.ExpertOpinInvestigDrugs.1998May;7(5):761-83.PMID:15991967.
