Clinafloxacin is a fluoroquinolone antibiotic that is clinically used to treat respiratory infections; it displays antibacterial efficacy by inhibiting DNA gyrase and topoisomerase IV. Clinafloxacin displays broad spectrum activity, inhibiting growth of Actinobacillus, Pasturella, Mannheima, and Histophilus.
| Cas No. | 105956-99-8 |
|---|---|
| Purity | ≥98% |
| Formula | C17H17ClFN3O3 • HCl |
| Formula Wt. | 402.24 |
| Chemical Name | 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride |
| IUPAC Name | 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid |
| Synonym | AM-1091; CI-960; PD-12739 |
| Melting Point | 263-265°C(dec.) |
| Appearance | Yellowish crystalline powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | C4535 MSDS PDF |
|---|---|
| Info Sheet | C4535 Info Sheet PDF |
Sweeney MT, Quesnell R, Tiwari R, et al. In vitro activity and rodent efficacy of clinafloxacin for bovine and swine respiratory disease. Front Microbiol. 2013 Jun 14;4:154. PMID: 23785362.
Ball P, Fernald A, Tillotson G. Therapeutic advances of new fluoroquinolones. Expert Opin Investig Drugs. 1998 May;7(5):761-83. PMID: 15991967.
