Clindamycinisalincosamideantibioticthatexhibitsantibacterial,anti-protozoan,anti-parasitic,andantimalarialactivities.Clindamycindisplaysefficacyagainstanaerobicgramnegativebacteria,Streptococcus,andStaphylococcus(particularlyMRSA).Clindamycinbinds23SrRNAoftheribosomal50Ssubunit,preventingtranslocationandproteinsynthesis.Whenco-admiNISTeredwithotheranti-parasiticcompounds,clindamycinisalsooccasionallyusedtotreatPlasmodiuminfection.
| CasNo. | 24729-96-2 |
|---|---|
| Purity | ≥95% |
| Formula | C18H34ClN2O8PS |
| FormulaWt. | 504.96 |
| IUPACName | [(2R,3R,4S,5R,6R)-6-[(1S,2S)-2-chloro-1-[[(2S,4R)-1-methyl-4-propylpyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyloxan-3-yl]dihydrogenphosphate |
| Synonym | 7(S)-Chloro-7-deoxylincomycin2-phosphate;Cleocinphosphate;Clindamycin-2-phosphate |
| MeltingPoint | 114°C |
| Solubility | Solubleinwater(400mg/mL).Insolubleinethanol. |
| Appearance | WhiteCrystalPowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | C4533MSDSPDF |
|---|---|
| InfoSheet | C4533InfoSheetPDF |
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