Description
Cloxacillin is a β-lactam antibiotic that displays antibacterial efficacy against a variety of species; it is especially active versus Staphylococcus. Like other β-lactam antibiotics, this compound binds penicillin binding proteins.
Cloxacillin is a β-lactam antibiotic that displays antibacterial efficacy against a variety of species; it is especially active versus Staphylococcus. Like other β-lactam antibiotics, this compound binds penicillin binding proteins.
Cas No. | 7081-44-9 |
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Purity | ≥98% |
Formula | C19H17ClN3NaO5S • H2O |
Formula Wt. | 475.88 |
Chemical Name | 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(3-(2-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)- |
IUPAC Name | sodium;(2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
Synonym | Bactopen; Cloxapen; Cloxypen; Ekvacillin; Orbenin; Methocillin-S. |
Melting Point | 170°C (dec) |
Solubility | Soluble in water, methanol, ethanol or pyridine. |
Appearance | White or Almost-White Crystalline Powder |
Store Temp | Ambient |
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Ship Temp | Ambient |
MSDS | C4756 MSDS PDF |
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Info Sheet | C4756 Info Sheet PDF |
Sawai T, Yamaguchi A. Mechanism of beta-lactamase inhibition: differences between sulbactam and other inhibitors. Diagn Microbiol Infect Dis. 1989 Jul-Aug;12(4 Suppl):121S-129S. PMID: 2591172.
Barza M. Antimicrobial spectrum, pharmacology and therapeutic use of antibiotics. Part 2: penicillins. Am J Hosp Pharm. 1977 Jan;34(1):57-67. PMID: 318800.