D-CycloserineisanantibioticcompoundthatexhibitsantibacterialactivityagainstMycobacteriumtuberculosis;itinhibitsD-Ala-D-Alaligase.Additionally,D-cycloserineactsasaglycinesitepartialagoNISTatNMDAreceptors,enhancingmemoryandlearningandpotentiallydisplayingantidepressantandcognitionenhancingactivities.
| CasNo. | 68-41-7 |
|---|---|
| Purity | ≥98% |
| Formula | C3H6N2O2 |
| FormulaWt. | 102.09 |
| ChemicalName | D-4-Amino-3-isoxazolidinone |
| IUPACName | (4R)-4-amino-1,2-oxazolidin-3-one |
| Synonym | Closina;Farmiserina;Micoserina;Oxamycin;SEROmycin. |
| MeltingPoint | 155-156°C |
| Solubility | Solubleinwater.Slightlysolubleinmethanolorpropyleneglycol. |
| Appearance | Whitepowder(maygraduallyturnblueovertime) |
| StoreTemp | 4°C |
|---|---|
| ShipTemp | Ambient |
| MSDS | C9610MSDSPDF |
|---|---|
| InfoSheet | C9610InfoSheetPDF |
DangYH,MaXC,ZhangJC,etal.TargetingofNMDAReceptorsintheTreatmentofMajorDepression.CurrPharmDes.2014Jan10.[Epubaheadofprint].PMID:24410564.
ProsserGA,deCarvalhoLP.MetabolomicsReveald-Alanine:d-AlanineLigaseAstheTargetofd-CycloserineinMycobacteriumtuberculosis.ACSMedChemLett.2013Dec12;4(12):1233-1237.PMID:24478820.
Portero-TresserraM,Martí-NicoloviusM,Guillazo-BlanchG,etal.D-cycloserineinthebasolateralamygdalapreventsextinctionandenhancesreconsolidationofodor-rewardassociativelearninginrats.NeurobiolLearnMem.2013Feb;100:1-11.PMID:23200640.
