Stavudineisanucleosideanalogofthymidinethatexhibitsantiviralactivity.StavudineisaninhibitorofreversetranscriptasethatintercalateswithDNAtoinhibitviralreplicationandgrowth.AdmiNISTrationofstavudinemayincreaselevelsofROSandmitochondrialdysfunctioninADIpocytes,leadingtoapoptosisanddecreasesinproliferation.Stavudineinducesautophagyinadipocytesaswell,resultinginlipidaccumulationandhepaticdysfunction.
| CasNo. | 3056-17-5 |
|---|---|
| Purity | ≥98% |
| Formula | C10H12N2O4 |
| FormulaWt. | 224.21 |
| ChemicalName | 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione |
| IUPACName | 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione |
| Synonym | d4T |
| MeltingPoint | 159-160°C |
| Solubility | Water |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | S7603InfoSheetPDF |
|---|---|
| Brochures | AntiviralsBooklet |
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