SulfamethoxazoleisasulfonamideantibioticthatcompetitivelyinhibitsPABA,preventingbacterialproductionoffolicacidandsynthesisofDNA.SulfamethoxazoledisplaysantibacterialactivityagainstStreptococcus,Staphylococcus,Escherichia,Haemophilus,andPneumocystis.
| CasNo. | 723-46-6 |
|---|---|
| Purity | ≥98% |
| Formula | C10H11N3O3S |
| FormulaWt. | 253.28 |
| ChemicalName | 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfon-amide |
| IUPACName | 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide |
| Synonym | Sulfisomezole;Sulfamethylisoxazole;Sulfamethoxizole;Gantanol;Sinomin |
| MeltingPoint | 169-172°C |
| Solubility | Insolubleinwater. |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | S8248InfoSheetPDF |
|---|
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GleckmanR,AlvarezS,JoubertDW.Drugtherapyreviews:trimethoprim-sulfamethoxazole.AmJHospPharm.1979Jul;36(7):893-906.PMID:382841.
LewisEL,LaceyRW.Presentsignificanceofresistancetotrimethoprimandsulphonamidesincoliforms,Staphylococcusaureus,andStreptococcusfaecalis.JClinPathol.1973Mar;26(3):175-80.PMID:4633678.
