Description
Raltegravir is an antiviral compound that inhibits HIV integrase; it is clinically used to treat HIV infection. In pre-clinical models, raltegravir decreases infection rates by preventing insertion of HIV-1 DNA into the host genome.
Raltegravir is an antiviral compound that inhibits HIV integrase; it is clinically used to treat HIV infection. In pre-clinical models, raltegravir decreases infection rates by preventing insertion of HIV-1 DNA into the host genome.
| Cas No. | 518048-05-0 |
|---|---|
| Purity | ≥99% |
| Formula | C20H21FN6O5 |
| Formula Wt. | 444.42 |
| IUPAC Name | N-(4-Fluorobenzyl)-5-hydroxy-1-methyl-2-(2-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}-2-propanyl)-6-oxo-1,6-dihydro-4-pyrimidinecarboxamide |
| Synonym | MK-0518 |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | R0247 Info Sheet PDF |
|---|---|
| Brochures | Antivirals Booklet |
Taramasso L, Madeddu G, Ricci E, et al. Raltegravir-based therapy in a cohort of HIV/HCV co-infected individuals. Biomed Pharmacother. 2015 Feb;69:233-6. PMID: 25661363.
Mouscadet JF, Tchertanov L. Raltegravir: molecular basis of its mechanism of action. Eur J Med Res. 2009 Nov 24;14 Suppl 3:5-16. PMID: 19959411.
Hicks C, Gulick RM. Raltegravir: the first HIV type 1 integrase inhibitor. Clin Infect Dis. 2009 Apr 1;48(7):931-9. PMID: 19231980.