LKT/S-(N-PHENYLBUTYLTHIOCARBAMOYL)-L-CYSTEINE/P2516/10 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/S-(N-PHENYLBUTYLTHIOCARBAMOYL)-L-CYSTEINE/P2516/10 mg

LKT/S-(N-PHENYLBUTYLTHIOCARBAMOYL)-L-CYSTEINE/P2516/10 mg

商品编号： P2516-10mg

品牌： lktlabs

市场价： ¥3140.00

美元价： 1884.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

ProductIDP2516

CasNo.

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

S-(N-Phenylbutylthiocarbamoyl)-L-cysteine(PBITC)isaconjugateofphenylbutylisothiocyanateandcysteine.IsothiocyanatesaretypicallyfoundinplantsoftheBrassicaceaefamily,includingbroccoli,cabbage,andrADIsh.Isothiocyanatesarebestknownfortheirantioxidative,anticancerchemotherapeutic,chemopreventive,anti-angiogenic,andantibioticproperties.Invitro,PBITCincreasescaspase3activityandcleavageofpoly(ADP)-ribosepolymerase(PARP),inducingcaspase-mediatedapoptosis.PBITCalsoinhibitsdevelopmentofpancreaticductaldysplasiasandadenocarcinomasanddecreasesoccurrenceoflungtumorsinanimalmodels.ThiscompounddecreasesoxidationofcarcinogenNNKandincreasesactivityofNADPH:quinoneoxidoreductaseandglutathione-S-transferaseinvitroandinvivo.

ProductInfo

Purity	≥98%
Formula	C₁₄H₂₀N₂O₂S₂
FormulaWt.	312.45
Synonym	Phenylbutylisothiocyanate-L-cysteine
Appearance	Whitetooffwhitepowder

ShippingandStorage

StoreTemp	-20°C
ShipTemp	Ambient

Downloads

InfoSheet	P2516InfoSheetPDF

References

SonHY,NishikawaA,FurukawaF,etal.Modifyingeffectsof4-phenylbutylisothiocyanateonN-nitrosobis(2-oxopropyl)amine-inducedtumOrigenesisinhamsters.CancerLett.2000Nov28;160(2):141-7.PMID:11053643.

YuR,MandlekarS,HarveyKJ,etal.Chemopreventiveisothiocyanatesinduceapoptosisandcaspase-3-likeproteaseactivity.CancerRes.1998Feb1;58(3):402-8.PMID:9458080.

GuoZ,SmithTJ,WangE,etal.Structure-activityrelationshipsofarylalkylisothiocyanatesfortheinhibitionof4-(methylnitrosamino)-1-(3-pyridyl)-1-butanonemetabolismandthemodulationofxenobiotic-metabolizingenzymesinratsandmice.Carcinogenesis.1993Jun;14(6):1167-73.PMID:8508504.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂