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商品详细LKT/SOFOSBUVIR/S5722/10 mg
LKT/SOFOSBUVIR/S5722/10 mg
LKT/SOFOSBUVIR/S5722/10 mg
商品编号: S5722-10mg
品牌: lktlabs
市场价: ¥3960.00
美元价: 2376.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References

Description

Sofosbuvir is an antiviral compound that inhibits viral RNA polymerase. Sofosbuvir is clinically used to treat hepatitis C infection. This compound is a prodrug that is metabolized to a more active intermediate.

Product Info

Cas No.

1190307-88-0

Purity

≥98%

Formula

C22H29FN3O9P

Formula Wt.

529.45

IUPAC Name

propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate

Appearance

Yellow to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

Info Sheet

S5722 Info Sheet PDF

References

Murakami C, Melda Urekli H, Atta MG. Antiviral medications for the treatment of hepatitis B and C infection and their effects on kidney function. Minerva Gastroenterol Dietol. 2014 Sep;60(3):177-89. PMID: 25027705.

Fung A, Jin Z, Dyatkina N, et al. Efficiency of incorporation and chain termination determines the inhibition potency of 2'-modified nucleotide analogs against hepatitis C virus polymerase. Antimicrob Agents Chemother. 2014 Jul;58(7):3636-45. PMID: 24733478.

Murakami E, Tolstykh T, Bao H, et al. Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977. J Biol Chem. 2010 Nov 5;285(45):34337-47. PMID: 20801890.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂