LKT/BRASSININ/B6801/100 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/BRASSININ/B6801/100 mg

LKT/BRASSININ/B6801/100 mg

商品编号： B6801-100mg

品牌： lktlabs

市场价： ¥5080.00

美元价： 3048.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDB6801

CasNo.105748-59-2

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Brassininisaphytoalexinoriginallyfoundincruciferousvegetables.Thisindoleexhibitsanticancerchemotherapeuticandchemopreventiveactivities.Inprostatecancercells,brassinininducesG1phasecellcyclearrestandapoptosis,decreasesthemitochondrialmembranepotential,suppressescaspase3andPARPactivation,andlimitsPI3K/Akt/mTORsignaling.Invivo,brassinininhibitsindoleamine2,3-dioxygenase,inducingregressionofmammaryglandtumors.Inotheranimalmodels,thiscompoundinhibitsDMBA-inducedskintumorformation.Likeothercompoundsproducedbycruciferousvegetables,brassininmayinducephaseIIenzymes,displayingpotentialantioxidativebenefit.

ProductInfo

CasNo.	105748-59-2
Purity	≥98%
Formula	C₁₁H₁₂N₂S₂
FormulaWt.	236.36
ChemicalName	methyl(1H-indol-3-ylmethylamino)methanedithioate
IUPACName	methylN-(1H-indol-3-ylmethyl)carbamodithioate
Synonym	methylN-(1H-indol-3-ylmethyl)-carbamodithioate
MeltingPoint	132-133°C
Solubility	SolubleinDMSO.
Appearance	WhiteCrystalPowder

ShippingandStorage

StoreTemp	-20°C
ShipTemp	Ambient

Downloads

MSDS	B6801MSDSPDF
InfoSheet	B6801InfoSheetPDF

References

KimSM,ParkJH,KimKD,etal.BrassinininducesapoptosisinPC-3humanprostatecancercellsthroughthesuppressionofPI3K/Akt/mTOR/S6K1signalingcascades.PhytotherRes.2014Mar;28(3):423-31.PMID:23686889.

BanerjeeT,DuhadawayJB,GaspariP,etal.Akeyinvivoantitumormechanismofactionofnaturalproduct-basedbrassininsisinhibitionofindoleamine2,3-dioxygenase.Oncogene.2008May1;27(20):2851-7.PMID:18026137.

MehtaRG,LiuJ,ConstantinouA,etal.Cancerchemopreventiveactivityofbrassinin,aphytoalexinfromcabbage.Carcinogenesis.1995Feb;16(2):399-404.PMID:7859373.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂