Description
Calphostin C is an inhibitor of PKC found in Cladosporium. Calphostin C exhibits anticancer activity, inducing apoptosis, increasing JNK and caspase activation, and stimulating PARP cleavage in breast cancer cells.
LKT/CALPHOSTIN C/C0344/100 µg
商品编号：
C0344-100µg
品牌：
lktlabs
市场价：
¥8960.00
美元价：
5376.00
产品分类：
临床研究
公司分类：
clinical_research
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product ID C0344
Cas No. 121263-19-2
Purity ≥95%
- Description
- Product Info
- Shipping and Storage
- Downloads
- References
Product Info
| Cas No. | 121263-19-2 |
|---|---|
| Purity | ≥95% |
| Formula | C44H38O14 |
| Formula Wt. | 790.76 |
| IUPAC Name | 1-[3,10-dihydroxy-12-[2-(4-hydroxyphenoxy)carbonyloxypropyl]-2,6,7,11-tetramethoxy-4,9-dioxoperylen-1-yl]propan-2-yl benzoate |
| Synonym | UCN-1028c |
| Solubility | Soluble in DMSO, ethanol, or DMF. |
| Appearance | Dark Red Solid |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | C0344 MSDS PDF |
|---|---|
| Info Sheet | C0344 Info Sheet PDF |
References
De Vita F, Riccardi M, Malanga D, et al. PKC-dependent phosphorylation of p27 at T198 contributes to p27 stabilization and cell cycle arrest. Cell Cycle. 2012 Apr 15;11(8):1583-92. PMID: 22441823.
Robitaille K, Daviau A, Lachance G, et al. Calphostin C-induced apoptosis is mediated by a tissue transglutaminase-dependent mechanism involving the DLK/JNK signaling pathway. Cell Death Differ. 2008 Sep;15(9):1522-31. PMID: 18497756.
Kobayashi E, Ando K, Nakano H, et al. Calphostins (UCN-1028), novel and specific inhibitors of protein kinase C. I. Fermentation, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo). 1989 Oct;42(10):1470-4. PMID: 2478514.
品牌介绍
LKT Labs
LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。
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