Tenuazonicacid(TA)isamycotoxininitiallyproducedbyAlternariafungiandoccursprimarilyingrains.TAinhibitsphotosynthesisinchloroplastsandincreasesgenerationofROSsuchashydrogenperoxide,superoxiderADIcals,andhydroxideradicals,resultingincelldestructionandleafnecrosis.
| CasNo. | 610-88-8 |
|---|---|
| Purity | ≥96% |
| Formula | C10H15NO3 |
| FormulaWt. | 197.23 |
| IUPACName | 4-acetyl-2-butan-2-yl-3-hydroxy-1,2-dihydropyrrol-5-one |
| Synonym | 3-Pyrrolin-2-one,3-acetyl-5-sec-butyl-4-hydroxy-,L-L-Tenuazonicacid |
| Solubility | SolubleinDMSOandethanol. |
| Appearance | BlueGreenPowder |
| StoreTemp | 4°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | T1952InfoSheetPDF |
|---|
SchwarzC,KreutzerM,MarkoD.Minorcontributionofalternariol,alternariolmonomethyletherandtenuazonicacidtothegenotoxicpropertiesofextractsfromAlternariaalternatainfestedrice.ToxicolLett.2012Oct2;214(1):46-52.PMID:22906495.
ChenS,YinC,QiangS,etal.Chloroplasticoxidativeburstinducedbytenuazonicacid,anaturalphotosynthesisinhibitor,triggerscellnecrosisinEupatoriumadenophorumSpreng.BiochimBiophysActa.2010Mar;1797(3):391-405.PMID:20026008.
