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当前位置: 首页 > 产品中心 > clinical_research > LKT/SESAMIN/S1872/5 mg
商品详细LKT/SESAMIN/S1872/5 mg
LKT/SESAMIN/S1872/5 mg
LKT/SESAMIN/S1872/5 mg
商品编号: S1872-5mg
品牌: lktlabs
市场价: ¥1940.00
美元价: 1164.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

SesaminisaligninextractedfromtheseedsoftheSesaminindicumplant.Sesaminexhibitsantioxidativeandanticanceractivities.Incellularmodels,sesaminsuppressesSTAT3signaling,promotingcellcyclearrestandapoptosisofhepatocellularcarcinomacells.ThiscompoundactivatesERK/MAPKandp38signalingtoinduceosteoblastdifferentiationinvitroandreversespathologicalchangesassociatedwithosteoarthritisinvivo.Sesaminalsoprotectsagainstoxidativestressinspontaneouslyhypertensiveratsandanimalmodelsofoxidativeliverdamage.

ProductInfo

CasNo.

607-80-7

Purity

≥98%

Formula

C20H18O6

FormulaWt.

354.35

ChemicalName

5,5"-(1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diylbis(1,3-benzodioxole)

IUPACName

5-[(3S,3aR,6S,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-1,3-benzodioxole

MeltingPoint

114-129°C

Appearance

Whitetooffwhitepowder

ShippingandStorage

StoreTemp

-20°C

ShipTemp

BlueIce

Downloads

InfoSheet

S1872InfoSheetPDF

References

DengP,WangC,ChenL,etal.SesaminInducesCellCycleArrestandApoptosisthroughtheInhibitionofSignalTransducerandActivatorofTranscription3SignallinginHumanHepatocellularCarcinomaCellLineHepG2.BiolPharmBull.2013;36(10):1540-1548.PMID:24088253.

LiuCM,ZhengGH,MingQL,etal.Sesaminprotectsmouseliveragainstnickel-inducedoxidativeDNAdamageandapoptosisbythePI3K-Aktpathway.JAgricFoodChem.2013Feb6;61(5):1146-54.PMID:23317420.

LiWX,KongX,ZhangJX,etal.Long-termintakeofsesaminimprovesleftventricularremodellinginspontaneouslyhypertensiverats.FoodFunct.2013Feb26;4(3):453-60.PMID:23238059.

PhitakT,PothacharoenP,SettakornJ,etal.Chondroprotectiveandanti-inflammatoryeffectsofsesamin.Phytochemistry.2012Aug;80:77-88.PMID:22704650.

WanachewinO,BoonmaleeratK,PothacharoenP,etal.Sesaminstimulatesosteoblastdifferentiationthroughp38andERK1/2MAPKsignalingpathways.BMCComplementAlternMed.2012May30;12:71.PMID:22646286.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂