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当前位置: 首页 > 产品中心 > clinical_research > LKT/CAPSAICIN, NATURAL/C0266/1 g
商品详细LKT/CAPSAICIN, NATURAL/C0266/1 g
LKT/CAPSAICIN, NATURAL/C0266/1 g
LKT/CAPSAICIN, NATURAL/C0266/1 g
商品编号: C0266-1g
品牌: lktlabs
市场价: ¥3740.00
美元价: 2244.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

CapsaicinisanagoNISToftransientreceptorpotentialvanilloid(TRPV)channelsthatwasoriginallyfoundinpeppersoftheCapsicumgenus.Capsaicinexhibitsanalgesic,anti-inflammatory,anti-obesity,andanticancerchemotherapeuticactivity.Capsaicinalsodisplaysbronchoconstrictiveactivityandisusedasanaturalirritant.Invivo,thiscompounddesensitizesTRPV1channels,inhibitingthermalandmechanicalhyperalgesia.Inotheranimalmodels,capsaicininhibitsADIpogenesis,decreasesmetabolicdysregulation,activatesPPARα,andsuppressesweightgainandfatdeposition.CapsaicinalsoinducesapoptosisviaROSanddisruptionofthemitochondrialmembraneandinhibitstumorgrowthincellularandanimalmodelsofprostatecancer,breastcancer,pancreaticcancer,andhepatocellularcarcinoma.Thismixturecontainscapsaicin,≥65%,dihydrocapsaicin,~20%,andnordihydrocapsaicin,~4%.

ProductInfo

CasNo.

404-86-4

Purity

≥95%

Formula

C18H27NO3

FormulaWt.

305.41

ChemicalName

(6E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide

IUPACName

(E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide

Synonym

Axsain;Mioton;Zacin;Zostrix

MeltingPoint

65°C

Solubility

Solubleinether,benzene,andchloroform.Practicallyinsolubleincoldwater.

Appearance

Slightyellowish-whitepowder

ShippingandStorage

StoreTemp

4°C

ShipTemp

Ambient

Downloads

MSDS

C0266MSDSPDF

InfoSheet

C0266InfoSheetPDF

Brochures

TRPChannelModulatorFlyer

References

Díaz-LaviadaI,Rodríguez-HencheN.Thepotentialantitumoreffectsofcapsaicin.ProgDrugRes.2014;68:181-208.PMID:24941670.

LeungFW.Capsaicinasananti-obesitydrug.ProgDrugRes.2014;68:171-9.PMID:24941669.

KissinI.Vanilloid-inducedconductionanalgesia:selective,dose-dependent,long-lasting,withalowlevelofpotentialneurotoxicity.AnesthAnalg.2008Jul;107(1):271-81.PMID:18635498.

JensenPG,CurtisPD,DunnJA,etal.Fieldevaluationofcapsaicinasarodentaversionagentforpoultryfeed.PestManagSci.2003Sep;59(9):1007-15.PMID:12974352.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂