Tranylcypromine is an inhibitor of monoamine oxidase (MAO) that is clinically used to treat depression and anxiety. Tranylcypromine exhibits antidepressant and anxiolytic activities. This compound also inhibits histone demethylase LSD1, which has a similar sequence homology to MAOs.
| Cas No. | 1986-47-6 |
|---|---|
| Purity | ≥98% |
| Formula | C9H11N • HCl |
| Formula Wt. | 169.66 |
| Chemical Name | (1R,2S)-rel-2-Phenylcyclopropylamine hydrochloride |
| IUPAC Name | 2-phenylcyclopropan-1-amine;hydrochloride |
| Synonym | SKF-385 |
| Melting Point | 164-166°C |
| Appearance | Light Yellow Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | T6903 MSDS PDF |
|---|---|
| Info Sheet | T6903 Info Sheet PDF |
Lee MG, Wynder C, Schmidt DM, et al. Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications. Chem Biol. 2006 Jun;13(6):563-7. PMID: 16793513.
Preskorn SH. Recent pharmacologic advances in antidepressant therapy for the elderly. Am J Med. 1993 May 24;94(5A):2S-12S. PMID: 8503477.
