Description
Brainnatriureticpeptide(BNP)bindsthenatriureticpeptidereceptortypeB(NPR-B)toexertcardiomodulatoryactivity.BNPissecretedbytheheart;itdisplayslipolyticeffects,contributingtofattyacidmobilizationincongestiveheartfailure.HighlevelsofBNParepredictiveofcardiovascularproblemssuchasheartfailureandstroke.BNPalsoinhibitsdenovocollagensynthesis,increasingexpressionofmatrixmetalloproteinases1,2,and3invitro.
References
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