Description
Thispeptideinhibitscalcineurinphosphataseactivityandisusedtoexaminetheeffectsofcalcineurininresearchstudies.Incellularmodels,thispeptideinhibitscalcineurin-inducedglutamate-mediatedneuronalcelldeathanddecreasesL-typeCa2+channelcurrents.
Thispeptideinhibitscalcineurinphosphataseactivityandisusedtoexaminetheeffectsofcalcineurininresearchstudies.Incellularmodels,thispeptideinhibitscalcineurin-inducedglutamate-mediatedneuronalcelldeathanddecreasesL-typeCa2+channelcurrents.
Purity | ≥95% |
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Formula | C124H205N39O39S2 |
FormulaWt. | 2930.38 |
Appearance | Whitetooffwhitepowder |
StoreTemp | -20°C |
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ShipTemp | Ambient |
InfoSheet | C0247InfoSheetPDF |
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TeradaH,MatsushitaM,LuYF,etal.Inhibitionofexcitatoryneuronalcelldeathbycell-permeablecalcineurinautoinhibitorypeptide.JNeuRochem.2003Dec;87(5):1145-51.PMID:14622094.
NorrisCM,BlalockEM,ChenKC,etal.CalcineurinenhancesL-typeCa(2+)channelactivityinhippocampalneurons:increasedeffectwithageinculture.Neuroscience.2002;110(2):213-25.PMID:11958864.
PerrinoBA.Regulationofcalcineurinphosphataseactivitybyitsautoinhibitorydomain.ArchBiochemBiophys.1999Dec1;372(1):159-65.PMID:10562429.