Calcitoningene-relatedpeptide(CGRP)(8-37)inhibitstheCGRPreceptorandisusedinresearchstudiestoexaminetheeffectsofCGRP.CGRP(8-37)inhibitstheeffectsofghrelinandinducescaspase3-mediatedapoptosisinretinalcellsofanimalmodelsofcoronaryarteryocclusion.LikeCGRP,thisfragmentlikelybindsRAMP1andCGRPreceptors.
| CasNo. | 119911-68-1 |
|---|---|
| Purity | ≥95% |
| Formula | C139H230N44O38 |
| FormulaWt. | 3125.65 |
| IUPACName | L-Valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanylglycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-serylglycylglycyl-L-valyl-L-valyl-L-lysyl-L-asparaginyl-L-asparaginyl-L-phenylalanyl-L-valyl-L-prolyl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-lysyl-L-alanyl-L-phenylalaninamide |
| Synonym | CGRP(8-37) |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | C0243InfoSheetPDF |
|---|
NguyenVT,WuY,GuilloryAN,etal.Delta-opioidaugmentscardiaccontractionthroughβ-adrenergicandCGRP-receptorco-signaling.Peptides.2012Jan;33(1):77-82.PMID:22108711.
YangJH,ZhangYQ,GuoZ.EndogenousCGRPprotectsretinalcellsagainststressinducedapoptosisinrats.NeurosciLett.2011Aug26;501(2):83-5.PMID:21763400.
