4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:防癌抗癌特殊化学品试剂
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > peptides > LKT/RGD-4C/R2510/5 mg
商品详细LKT/RGD-4C/R2510/5 mg
LKT/RGD-4C/R2510/5 mg
LKT/RGD-4C/R2510/5 mg
商品编号: R2510-5mg
品牌: lktlabs
市场价: ¥13600.00
美元价: 8160.00
产地: 美国(厂家直采)
公司:
产品分类: 多肽
公司分类: peptides
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References

Description

RGD-4C is a cell-adhesive peptide that binds αvβ3 and αvβ5 integrins; these integrins are overexpressed in many cancers and growing vessels, so RGD-4C is often attached to viral treatments to better deliver or target the treatment to cancerous tissues. RGD-4C exhibits anticancer chemotherapeutic and anti-angiogenic benefits in models of various cancers, including non-small cell lung cancer (NSCLC), melanoma, and glioma.

Product Info

Purity

≥95%

Formula

C42H60N14O16S4

Formula Wt.

1145.29

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

R2510 Info Sheet PDF

References

Allaume X, El-Andaloussi N, Leuchs B, et al. Retargeting of rat parvovirus H-1PV to cancer cells through genetic engineering of the viral capsid. J Virol. 2012 Apr;86(7):3452-65. PMID: 22258256.

Pesonen S, Diaconu I, Cerullo V, et al. Integrin targeted oncolytic adenoviruses Ad5-D24-RGD and Ad5-RGD-D24-GMCSF for treatment of patients with advanced chemotherapy refractory solid tumors. Int J Cancer. 2012 Apr 15;130(8):1937-47. PMID: 21630267.

Sarkioja M, Kanerva A, Salo J, et al. Noninvasive imaging for evaluation of the systemic delivery of capsid-modified adenoviruses in an orthotopic model of advanced lung cancer. Cancer. 2006 Oct 1;107(7):1578-88. PMID: 16948124.

Van Houdt WJ, Haviv YS, Lu B, et al. The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma. J Neurosurg. 2006 Apr;104(4):583-92. PMID: 16619663.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂