Description
AZD-8330 is an inhibitor of MEK1/2 that exhibits anticancer chemotherapeutic activity. AZD-8330 is currently in clinical trials for the treatment of advanced stage cancers.
AZD-8330 is an inhibitor of MEK1/2 that exhibits anticancer chemotherapeutic activity. AZD-8330 is currently in clinical trials for the treatment of advanced stage cancers.
Cas No. | 869357-68-6 |
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Purity | ≥98% |
Formula | C16H17FlN3O4 |
Formula Wt. | 461.23 |
IUPAC Name | 2-(2-fluoro-4-iodoanilino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxopyridine-3-carboxamide |
Synonym | ARRY-704, ARRY-424704 |
Appearance | White Powder |
Store Temp | -20°C |
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Ship Temp | Ambient |
Info Sheet | A9715 Info Sheet PDF |
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Brochures | Ras-Raf-MEK-ERK Pathway Booklet |
Cohen RB, Aamdal S, Nyakas M, et al. A phase I dose-finding, safety and tolerability study of AZD8330 in patients with advanced malignancies. Eur J Cancer. 2013 May;49(7):1521-9. PMID: 23433846.
Akinleye A, Furqan M, Mukhi N, et al. MEK and the inhibitors: from bench to bedside. J Hematol Oncol. 2013 Apr 12;6:27. PMID: 23587417.