Description
BI-2536isapolo-likekinase1(PLK1)inhibitorthatdisruptsmitosisandcelldivision.BI-2536exhibitsanticanceractivityandmayinduceapoptosisincancercells.
BI-2536isapolo-likekinase1(PLK1)inhibitorthatdisruptsmitosisandcelldivision.BI-2536exhibitsanticanceractivityandmayinduceapoptosisincancercells.
CasNo. | 755038-02-9 |
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Purity | ≥98% |
Formula | C28H39N7O3 |
FormulaWt. | 521.65 |
Synonym | BI2536 |
Appearance | Paleyellowtooff-whitepowder |
StoreTemp | -20°C |
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ShipTemp | Ambient |
InfoSheet | B3200InfoSheetPDF |
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ColnaghiR,WheatleySP.LiaisonsbetweensurvivinandPlk1duringcelldivisionandcelldeath.JBiolChem.2010Jul16;285(29):22592-604.PMID:20427271.
ZhangJ,YangPL,GrayNS.Targetingcancerwithsmallmoleculekinaseinhibitors.NatureReviewsCancer.2009Jan;9:28-39.