Salbutamolisashort-actingagoNISTatβ2-adrenergicreceptorsthatisclinicallyusedtotreatasthmaandchronicobstructivepulmonarydisorder(COPD).Salbutamolexhibitsbronchodilatory,anti-asthma,tocolytic,antioxidative,andanti-inflammatoryactivities.Invivo,salbutamoldecreasescarrageenan-inducedinflammationandnociception,suppressesactivityofmyeloperoxidase,andincreasesactivityofsuperoxidedismutaseandlevelsofglutathione.
| CasNo. | 51022-70-9 |
|---|---|
| Purity | ≥98% |
| Formula | (C13H21NO3)2•H2SO4 |
| FormulaWt. | 576.70 |
| ChemicalName | α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanolsulfate |
| IUPACName | 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol;sulfuricacid |
| Synonym | Aerolin;Asmaven;Ecovent;Loftan;Salbumol;Salbuvent;Venetlin;Volmax;salbutamolhemisulfate |
| MeltingPoint | 180°C |
| Solubility | Solubleinwater.Slightlysolubleinethanol. |
| Appearance | White-almostwhitecrystallinepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | S0045MSDSPDF |
|---|---|
| InfoSheet | S0045InfoSheetPDF |
MatsumotoK,AizawaH,FukuyamaS,etal.Low-dosesalbutamolsuppressesairwayresponsivenesstohistaminebutnotmethacholineinsubjectswithasthma.RespirInvestig.2013Sep;51(3):158-65.PMID:23978642.
UzkeserH,CADIrciE,HaliciZ,etal.Anti-inflammatoryandantinociceptiveeffectsofsalbutamolonacuteandchronicmodelsofinflammationinrats:involvementofanantioxidantmechanism.MediatorsInflamm.2012;2012:438912.PMID:22665951.
