Fenoldopam is a benzazepine derivative that acts as a partial agonist at D1 receptors; it may also inhibit α1-adrenergic receptors. Fenoldopam exhibits vasodilatory, antihypertensive, and natriuretic activities. In vivo, fenoldopam decreases blood pressure, afterload, and blood flow; it also inhibits NaCl reabsorption in the thick ascending limb, promoting Na+ excretion.
| Cas No. | 67227-57-0 |
|---|---|
| Purity | ≥98% |
| Formula | C16H16ClNO3S • CH3SO3H |
| Formula Wt. | 401.87 |
| Chemical Name | 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H- 3-benzazepine-7,8-diol methanesulfonate |
| IUPAC Name | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid |
| Synonym | Fenoldopam methanesulfonate; Corlopam |
| Melting Point | 274°C (dec) |
| Solubility | Soluble in water. DMSO 15 mg/mL. |
| Appearance | White to off white powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | F1654 MSDS PDF |
|---|---|
| Info Sheet | F1654 Info Sheet PDF |
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