Glucagon is an endogenous pancreatic peptide hormone that binds glucagon receptors to increase glucose levels and counteract the effects of insulin. Glucagon is clinically used to treat severe hypoglycemia and anaphylactic shock. Glucagon exhibits some antihypertensive activity, decreasing blood pressure.
| Cas No. | 16941-32-5 |
|---|---|
| Purity | ≥98% |
| Formula | C153H225N43O49S |
| Formula Wt. | 3482.78 |
| Synonym | Glukagon; HG-factor; Glucagon (1-29), human, bovine, porcine. |
| Solubility | Practically insoluble in water. Soluble in acidic or basic media. |
| Appearance | White to off-white Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | G4480 Info Sheet PDF |
|---|
Xu E, Kumar M, Zhang Y, et al. Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system. Cell Metab. 2006 Jan;3(1):47-58. PMID: 16399504.
Tang AW. A practical guide to anaphylaxis. Am Fam Physician. 2003 Oct 1;68(7):1325-32. Erratum in: Am Fam Physician. 2004 Mar 1;69(5):1049. PMID: 14567487.
White CM. A review of potential cardiovascular uses of intravenous glucagon administration. J Clin Pharmacol. 1999 May;39(5):442-7. PMID: 10234590.
