HelospectinIisapeptideoriginallyfoundinHelodermalizards.HelospectinIisaneuropeptideofthevasoactiveintestinalpeptide(VIP)familythatexhibitsvasodilatoryandantihypertensiveactivities,decreasingbloodpressureinvivo.Additionally,helospectinIincreasesplasmaglucagoninanimalmodels.
| CasNo. | 93438-37-0 |
|---|---|
| Purity | ≥95% |
| Formula | C183H293N47O59 |
| FormulaWt. | 4095.66 |
| Synonym | Exendin1 |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | H1645InfoSheetPDF |
|---|
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UddmanR,GoadsbyPJ,Jansen-OlesenI,etal.Helospectin-likepeptides:immunochemicallocalizationandeffectsonisolatedcerebralarteriesandonlocalcerebralbloodflowinthecat.JCerebBloodFlowMetab.1999Jan;19(1):61-7.PMID:9886356.
AhrénB.EffectsofhelospectinIoninsulinandglucagonsecretioninthemouse.BrJPharmacol.1991Apr;102(4):916-8.PMID:1855119.
GrundemarL,HögestättED.Vasculareffectsofhelodermin,helospectinIandhelospectinII:acomparisonwithvasoactiveintestinalpeptide(VIP).BrJPharmacol.1990Mar;99(3):526-8.PMID:2331581.
