LKT/HEXARELIN/H1893/5毫克-免疫在线蚂蚁淘旗下平台

商品详细LKT/HEXARELIN/H1893/5毫克

LKT/HEXARELIN/H1893/5毫克

商品编号： H1893-5mg

品牌： lktlabs

市场价： ¥14100.00

美元价： 8460.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Product ID H1893

Cas No. 140703-51-1

Purity ≥95%

Description
Product Info
Shipping and Storage
Downloads
References

Description

Hexarelin is a synthetic analog of ghrelin that binds and activates the ghrelin (GHS) receptor. Hexarelin exhibits cardioprotective, anti-fibrotic, antihypertensive, and anti-fertility activities. In animal models of myocardial infarction, hexarelin protects cardiac function. In spontaneously hypertensive rats, hexarelin prevents deposition of collagen, decreases expression of TIMP-1, collagen I, and collagen III, and increases expression of MMP2 and MMP9, decreasing cardiac fibrosis and blood pressure and attenuating left ventricular hypertrophy. Hexarelin also decreases ovulation and number of offspring produced in vivo.

Product Info

Cas No.	140703-51-1
Purity	≥95%
Formula	C₄₇H₅₈N₁₂O₆
Formula Wt.	887.0
Chemical Name	L-histidyl-2-methyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-Lysinamide
IUPAC Name	(2S)-6-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(2-methyl-1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamideInChI: InChI=1S/C47H58N12O6/c1-27-34(33-15-7-9-17-37(33)54-27)23-41(58-44(62)35(49)22-31-25-51-26-53-31)45(63)55-28(2)43(61)57-40(21-30-24-52-36-16-8-6-14-32(30)36)47(65)59-39(20-29-12-4-3-5-13-29)46(64)56-38(42(50)60)18-10-11-19-48/h3-9,12-17,24-26,28,35,38-41,52,54H,10-11,18-23,48-49H2,1-2H3,(H2,50,60)(H,51,53)(H,55,63)(H,56,64)(H,57,61)(H,58,62)(H,59,65)/t28-,35-,38-,39?,40-,41+/m0/s1
Synonym	Examorelin
Solubility	Soluble in water.
Appearance	White to Off-white Powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	H1893 MSDS PDF
Info Sheet	H1893 Info Sheet PDF

References

Mao Y, Tokudome T, Kishimoto I, et al. One dose of oral hexarelin protects chronic cardiac function after myocardial infarction. Peptides. 2014 Apr 18;56C:156-162. PMID: 24747279.

Xu X, Ding F, Pang J, et al. Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat. Am J Physiol Heart Circ Physiol. 2012 Sep 15;303(6):H703-11. PMID: 22842067.

Puechagut PB, Martini AC, Stutz G, et al. Reproductive performance and fertility in male and female adult mice chronically treated with hexarelin. Reprod Fertil Dev. 2012;24(3):451-60. PMID: 22401277.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂