Description
IdebenoneisasyntheticquinonecoenzymeQ(CoQ)analogthatpromotesmitochondrialrespiration,increasesATPproduction,andinhibitslipoperoxideformation.Idebenoneexhibitsantioxidative,neuroprotective,cognitionenhancing,cardioprotective,anti-inflammatory,andanti-fibroticactivities.InsubjectswithAlzheimer’sdiseaseandinanimalmodelsofscopolamine-inducedmemorydeficit,idebenoneimprovescognitivefunctionanddailylivingaspects.Additionally,idebenoneimprovesneurologicalfunctioninsubjectswithFriedreich’sataxia.InanimalmodelsofDuchennesMuscularDystrophy(DMD),idebenonedecreasescardiacinflammationandfibrosisandimprovescardiacdiastolicfunctionandexerciseperformance.
References
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