Ketoprofenisanon-steroidalanti-inflammatorydrug(NSAID)thatnon-selectivelyinhibitsCOX-1andCOX-2.Ketoprofenisclinicallyusedtotreatdentalandarthritispaininhumansandveterinarysubjects.Ketoprofenexhibitsanti-inflammatory,analgesic,antipyretic,anticoagulant,andimmunomodulatoryactivities.Ketoprofeninhibitslactatedehydrogenaseinplatelets,decreasingplateletcount.Inanimalmodelsofsepticlunginfection,ketoprofenincreasessurvivalratesaswellasmacrophagephagocytosisandneutrophilrecruitment.
| CasNo. | 22071-15-4 |
|---|---|
| Purity | ≥98% |
| Formula | C16H14O3 |
| FormulaWt. | 254.28 |
| ChemicalName | 3-Benzoyl-a-methylbenzeneaceticacid |
| IUPACName | 2-(3-benzoylphenyl)propanoicacid |
| Synonym | Ketofen;Ketopron |
| MeltingPoint | 93-96°C |
| Solubility | Solubleinethanol,acetoneorDMSO.Slightlysolubleinwater. |
| Appearance | Whiteoralmostwhitepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | K1677InfoSheetPDF |
|---|
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KantorTG.Ketoprofen:areviewofitspharmacologicandclinicalproperties.Pharmacotherapy.1986May-Jun;6(3):93-103.PMID:3526298.
