Description
Kyotorphinisanopioidneuropeptidethatexhibitsanalgesic,antinociceptive,vasodilatory,andantihypertensiveactivities.Kyotorphinbindsthekyotorphinreceptor,whichiscoupledtoGiGPCRs,alteringdownstreamPLCsignalingandmet-enkephalinrelease.
Kyotorphinisanopioidneuropeptidethatexhibitsanalgesic,antinociceptive,vasodilatory,andantihypertensiveactivities.Kyotorphinbindsthekyotorphinreceptor,whichiscoupledtoGiGPCRs,alteringdownstreamPLCsignalingandmet-enkephalinrelease.
CasNo. | 70904-56-2 |
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Purity | ≥95% |
Formula | C15H23N5O4 |
FormulaWt. | 337.4 |
IUPACName | (2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoicacid |
Appearance | Whitetooffwhitepowder |
StoreTemp | -20°C |
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ShipTemp | Ambient |
InfoSheet | K9858InfoSheetPDF |
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MiguelM,MansoM,AleixandreA,etal.Vasculareffects,angiotensinI-convertingenzyme(ACE)-inhibitoryactivity,andantihypertensivepropertiesofpeptidesderivedfromeggwhite.JAgricFoodChem.2007Dec26;55(26):10615-21.PMID:18047278.
UedaH,InoueM.Invivosignaltransductionofnociceptiveresponsebykyotorphin(tyrosine-arginine)throughGalpha(i)-andinositoltrisphosphate-mediatedCa(2+)influx.MolPharmacol.2000Jan;57(1):108-15.PMID:10617685.
SatohM,WadaT,IwamaT,etal.SitesofanalgesicactionsofkyotorphinandD-kyotorphininthecentralnervoussystemofrats.Neuropeptides.1985Feb;5(4-6):415-8.PMID:4000414.