Minoxidil is an NO agonist/donor that exhibits vasodilatory and antihypertensive activities; minoxidil is clinically used to treat hair loss, as its activity allows increased blood and nutrient flow to hair follicles. Minoxidil also binds the androgen receptor and inhibits androgen receptor-related functions.
| Cas No. | 38304-91-5 |
|---|---|
| Purity | ≥98% |
| Formula | C9H15N5O |
| Formula Wt. | 209.25 |
| Chemical Name | 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide |
| IUPAC Name | 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine |
| Synonym | Alopexil; Loniten; Minoximen; Normoxidil; Regaine; Rogaine Tricoxidil |
| Melting Point | 248°C °r 259-261°C(dec.) |
| Solubility | Soluble in propylene glycol, methanol or ethanol. Slightly soluble in water. |
| Appearance | White-almost white crystalline powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | M3453 Info Sheet PDF |
|---|
Hsu CL, Liu JS, Lin AC, et al. Minoxidil may suppress androgen receptor-related functions. Oncotarget. 2014 Apr 30;5(8):2187-97. PMID: 24742982.
Rossi A, Cantisani C, Melis L, et al. Minoxidil use in dermatology, side effects and recent patents. Recent Pat Inflamm Allergy Drug Discov. 2012 May;6(2):130-6. PMID: 22409453.
