S-(+)-Ibuprofenistheopticallyactiveisomerofibuprofen,anon-steroidalanti-inflammatorydrug(NSAID)thatnon-selectivelyinhibitsCOX-1andCOX-2.Ibuprofenexhibitsanti-inflammatory,antipyretic,analgesic,andneuroprotectiveactivities.ThiscompounddisplaysprotectiveefficacyagainstAlzheimer’sdiseasewhenadmiNISTeredclinically.
| CasNo. | 51146-56-6 |
|---|---|
| Purity | ≥98% |
| Formula | C13H18O2 |
| FormulaWt. | 206.28 |
| ChemicalName | (+)-2-(4-Isobutylphenyl)-propionicAcid |
| IUPACName | (2S)-2-[4-(2-methylpropyl)phenyl]propanoicacid |
| MeltingPoint | 51-53°C |
| Solubility | Solubleinmethanol,DMSOandethanol. |
| Appearance | Whitebulbcrystallinepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | I0482InfoSheetPDF |
|---|
VladSC,MillerDR,KowallNW,etal.ProtectiveeffectsofNSAIDsonthedevelopmentofAlzheimerdisease.Neurology.2008May6;70(19):1672-7.PMID:18458226.
VanEschA,VanSteensel-MollHA,SteyerbergEW,etal.Antipyreticefficacyofibuprofenandacetaminopheninchildrenwithfebrileseizures.ArchPediatrAdolescMed.1995Jun;149(6):632-7.PMID:7767417.
